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Sarcoidosis%u2022 Multi-system granulomatous disorder of unknown etiologyDefinition:%u2022 Pulmonary involvement (most common)%u2022 Skin lesions (erythema nodosum, lupus pernio)%u2022 Ocular involvement (uveitis)%u2022 Arthralgia/arthritis%u2022 Hepatosplenomegaly%u2022 Neurological involvementClinical features:%u2022 Chest X-ray: bilateral hilar lymphadenopathy%u2022 Elevated serum ACE levels%u2022 Hypercalcemia%u2022 Tissue biopsy: non-caseating granulomasInvestigations:%u2022 Often self-limiting, may not require treatment%u2022 Corticosteroids for symptomatic or progressive disease%u2022 Methotrexate, hydroxychloroquine as steroid-sparing agentsTreatment:
