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Gout%u2022Crystal-induced arthropathy due to deposition of monosodium urate (MSU) crystalsDefinition:%u2022Hyperuricemia%u2022Male gender%u2022Obesity%u2022Alcohol consumption%u2022Purine-rich diet%u2022Certain medications (diuretics, low-dose aspirin)Risk factors:%u2022Acute, severe joint pain and swelling (often first MTP joint)%u2022Erythema and warmth over affected joint%u2022Tophi in chronic goutClinical features:%u2022Synovial fluid analysis: MSU crystals (needle-shaped, negatively birefringent)%u2022Serum uric acid (may be normal during acute attack)Diagnosis:%u2022Acute attack: NSAIDs, colchicine, or corticosteroids%u2022Chronic management: Allopurinol, febuxostat (xanthine oxidase inhibitors)%u2022Lifestyle modifications: weight loss, limiting alcohol and purine-rich foodsTreatment:
