Page 39 - Demo
P. 39
Giant Cell Arteritis (Temporal Arteritis)%u2022Vasculitis of large and medium-sized arteries, typically affecting cranial arteriesDefinition:%u2022New-onset headache%u2022Scalp tenderness%u2022Jaw claudication%u2022Visual disturbances (risk of permanent vision loss)%u2022Polymyalgia rheumatica symptoms%u2022Constitutional symptoms (fever, weight loss, fatigue)Clinical features:%u2022Elevated ESR and CRP%u2022Temporal artery biopsy (gold standard)%u2022Color duplex ultrasonography of temporal arteries%u2022PET-CT for large vessel involvementInvestigations:%u2022High-dose corticosteroids (urgent treatment to prevent vision loss)%u2022Tocilizumab (IL-6 inhibitor) as steroid-sparing agent%u2022Low-dose aspirin for cardiovascular protectionTreatment:
