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Beh%u00e7et's Disease%u2022Multi-system inflammatory disorder characterized by recurrent oral and genital ulcersDefinition:%u2022Recurrent oral aphthous ulcers (required for diagnosis)%u2022Genital ulcers%u2022Ocular involvement (uveitis, retinal vasculitis)%u2022Skin lesions (erythema nodosum, papulopustular lesions)%u2022Arthritis%u2022Vascular involvement (arterial and venous thrombosis)%u2022Neurological involvementClinical features:%u2022Pathergy test (skin hyperreactivity to needle prick)Diagnostic test:%u2022Topical corticosteroids for mucocutaneous lesions%u2022Colchicine for mucocutaneous and joint involvement%u2022Systemic immunosuppression for severe organ involvement (e.g., azathioprine, cyclosporine)%u2022Anti-TNF therapy for refractory casesTreatment:
