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Necrotising Fasciitis%u2022Mainly caused by group A beta-hemolytic streptococci%u2022Infection spreads deep, involving dermis, subcutaneous tissues, fascia, and muscles%u2022Life-threatening and rapidly spreadingFacts:%u2022IM and SC injections, immunosuppression, diabetesRisk factors:%u2022Initial stage (1-2 days):%u2022Presents as cellulitis: erythema, swelling, pain over affected area(s)%u2022Progressive stage:%u2022Bullae formation%u2022Grey/black skin (necrosis)%u2022Hard subcutaneous tissue%u2022Advanced stage:%u2022Septic shock%u2022Severe painClinical Presentation:%u2022Urgent surgical debridement%u2022IV antibiotics: clindamycin or benzylpenicillin%u2022Note: Does NOT respond to flucloxacillinTreatment:%u2022Differs from erysipelas as necrotising fasciitis is diffuse and deep%u2022Erysipelas is a well-demarcated infectionKey Distinction:
