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SLE: Investigations and ManagementInvestigations:ANA (high sensitivity)Anti-dsDNA antibody (high specificity)Complement levels (C3 and C4): Often decreasedComplete blood count, renal function testsManagement:Hydroxychloroquine: For skin lesions, arthralgia, myalgia, oral ulcersNSAIDs: For arthralgia and myalgiaCorticosteroids: For severe casesImmunosuppressants(e.g., cyclophosphamide): For life-threatening complications
