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Respiratory Acidosis vs. Respiratory Alkalosis: Key DifferencesCharacteristic Respiratory Acidosis Respiratory AlkalosisDefinition Excess CO2 retention Excess CO2 eliminationpH Decreased (< 7.35) Increased (> 7.45)PaCO2 Increased (> 45 mmHg) Decreased (< 35 mmHg)Common Causes %u2022 COPD exacerbation %u2022 Anxiety, panic%u2022 Severe asthma %u2022 Pain, fever%u2022 CNS depression %u2022 Mechanical%u2022 Neuromuscular overventilationdisorders %u2022 Early salicylatepoisoningCompensatory Metabolic alkalosis Metabolic acidosisMechanism (%u2191 HCO3-) (%u2193 HCO3-)Clinical %u2022 Drowsiness %u2022 LightheadednessSymptoms %u2022 Confusion %u2022 Paresthesias%u2022 Headache %u2022 TetanyTreatment %u2022 Treat underlying %u2022 Treat underlyingApproach cause cause%u2022 Improve ventilation %u2022 Normalize breathing%u2022 O2 therapy pattern%u2022 Mechanical %u2022 Adjust ventilatorventilation if settings ifsevere applicable