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Duodenal Atresia%u2022 Definition:%u2022 Congenital obstruction of the duodenum, typically occurring in the second part%u2022 Epidemiology:%u2022 Incidence: 1 in 5,000-10,000 live births%u2022 Associated with Down syndrome in 30% of cases%u2022 Pathophysiology:%u2022 Failure of recanalization of the duodenal lumen during fetal development%u2022 Clinical Presentation:%u2022 Polyhydramnios in prenatal ultrasound%u2022 Bilious vomiting within first 24-48 hours of life%u2022 Upper abdominal distension

