Page 96 - Demo

Key Differences Between Case StudiesSLE vs. Other Conditions:%u2022Multisystem involvement (skin, joints, kidneys)%u2022Characteristic malar rash and photosensitivity%u2022Positive anti-dsDNA antibodiesPolymyositis vs. Dermatomyositis:%u2022Proximal muscle weakness without skin involvement%u2022Elevated creatine kinase and anti-Jo1 antibodiesSj%u00f6gren's Syndrome:%u2022Focuses on exocrine gland dysfunction (dry eyes, dry mouth)%u2022Positive anti-Ro and anti-La antibodiesGiant Cell Arteritis:%u2022Older age group (typically >50 years)%u2022Headache, scalp tenderness, jaw claudication%u2022Markedly elevated ESRSystemic Sclerosis:%u2022Skin thickening and tightening%u2022Raynaud's phenomenon%u2022Positive anti-Scl-70 antibodiesCeliac Disease:%u2022Gastrointestinal symptoms (chronic diarrhea, malabsorption)%u2022Positive anti-tissue transglutaminase antibodies%u2022Improvement with gluten-free dietGraves' Disease:%u2022Hyperthyroidism symptoms (weight loss, palpitations, heat intolerance)%u2022Eye involvement (exophthalmos)%u2022Positive TSH receptor antibodiesRheumatoid Arthritis:%u2022Symmetric polyarthritis, primarily small joints%u2022Positive rheumatoid factor and antiCCP antibodies%u2022Erosive changes on X-raysPolymyalgia Rheumatica:%u2022Shoulder and hip girdle pain and stiffness%u2022Rapid response to low-dose corticosteroids%u2022Very high ESR/CRP with normal creatine kinase