Page 41 - Demo

MCQ 3: Nausea in Brain TumorA 58-year-old woman with a newly diagnosed glioblastoma is experiencing persistent nausea and vomiting. CT scan shows increased intracranial pressure. Which medication is most appropriate as a first-line antiemetic?A. OndansetronB. MetoclopramideC. CyclizineD. HaloperidolE. DomperidoneAnswer: CyclizineExplanation: Cyclizine is the first-line antiemetic for nausea and vomiting secondary to increased intracranial pressure, as seen in brain tumors. It acts as an antihistamine and anticholinergic, effectively reducing nausea associated with vestibularstimulation and increased ICP. Ondansetron is more suitable for chemotherapy-induced nausea. Metoclopramide and domperidone are prokinetics, less effective for this etiology. Haloperidol is typically used for opioid-induced or metabolic causes of nausea in palliative care.