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                                    Question 12A patient with metastatic colorectal cancer develops severe diarrhea after starting capecitabine. What is the most appropriate next step?A. Continue treatment and add loperamideB. Reduce the dose of capecitabineC. Switch to 5-fluorouracilD. Stop capecitabine immediatelyE. Add probiotics to the treatment regimenAnswer: Stop capecitabine immediatelyExplanation: Severe diarrhea is a potentially lifethreatening side effect of capecitabine. The drug should be stopped immediately, and the patient should be assessed for dehydration and electrolyte imbalances.
                                
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