Page 94 - Demo

Leptospirosis (Weil's Disease)Transmission:%u2022 Direct: Contact with urine of infected animals%u2022 Indirect: Exposure to water contaminated by infected animal urineClinical Features:%u2022 History of travel and water exposure%u2022 Animal contact%u2022 Initial presentation: Red eyes (subconjunctival hemorrhage)%u2022 Later: Yellow eyes (jaundice)%u2022 Fever, rigors, malaise, arthralgia, myalgiaInvestigations:%u2022 Blood and urine culture and sensitivity%u2022 Detectable in blood: First 7-10 days of disease%u2022 Detectable in urine: After 7 days and up to 30 daysTreatment:%u2022 Self-limiting in mild cases%u2022 Oral doxycycline for mild cases%u2022 Ampicillin or benzylpenicillin for severe cases