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Diagnosis of Cushing's Syndrome%u2022 24-hour urinary free cortisol%u2022 Low-dose dexamethasone suppression testTo confirm Cushing's syndrome:%u2022 Plasma ACTH: High (ACTH-dependent) or Low (ACTH-independent)%u2022 If ACTH is high:%u2022 High-dose dexamethasone test%u2022 MRI pituitary%u2022 If ACTH is lo%u2022 CT or MRI scan of abdomen (look for adrenal tumor)To identify the cause:
