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Hyperthyroidism in PregnancyTreatment approach:%u2022 Pre-pregnancy and first trimester: Propylthiouracil%u2022 Second and third trimester: Carbimazole%u2022 Postpartum: CarbimazoleImportant notes:%u2022 Carbimazole: risk of aplasia cutis and omphalocele in the fetus%u2022 Propylthiouracil: risk of hepatotoxicity in the mother%u2022 Use lowest possible effective dose%u2022 Radioiodine therapy is contraindicated%u2022 Partial thyroidectomy may be considered in 2nd trimester if medical treatment fails

