Page 78 - Demo

Anaphylaxis vs. Hereditary AngioedemaComparison TableFeature Anaphylaxis Hereditary AngioedemaCause Allergic reaction (IgE-mediated) C1 esterase inhibitor deficiency (genetic)Onset Rapid (minutes to hours) Gradual (hours to days)Triggers Allergens (e.g., foods, drugs, insect stings) Stress, trauma, infections, hormonal changesUrticaria (hives) Common RareItching Prominent UncommonRespiratory symptoms Bronchospasm, wheezing Upper airway edema (no wheezing)Gastrointestinal symptoms Nausea, vomiting, diarrhea Severe abdominal pain, vomitingHypotension Common Can occur, but less commonFamily history Not typically relevant Often presentResponse to antihistamines Often helpful Not effectiveResponse to epinephrine Effective Not effectiveFirst-line treatment IM epinephrine C1 inhibitor concentrate or bradykinin receptor antagonist