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Case Study 5: Serotonin Syndrome%u2022 35-year-old female on fluoxetine, recently started St. John's WortPatient:%u2022 Agitation, confusion, sweating, tremor, hyperreflexia, temperature 39%u00b0CPresentation:%u2022 Discontinuation of fluoxetine and St. John's Wort%u2022 IV fluids for hydration%u2022 Benzodiazepines (diazepam) for agitation%u2022 Cyproheptadine 12mg orally, then 2mg every 2 hours%u2022 Active cooling measures%u2022 Monitoring in ICU for 24 hours%u2022 Psychiatry consultation for future antidepressant managementTreatment
